Results 61 to 70 of about 8,127,621 (365)

Web searching for systematic reviews: a case study of reporting standards in the UK Health Technology Assessment programme

BMC Research Notes, 2015
BackgroundIdentifying literature for a systematic review requires searching a variety of sources. The main sources are typically bibliographic databases. Web searching using search engines and websites may be used to identify grey literature.
S. Briscoe
semanticscholar   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

SMART on FHIR: a standards-based, interoperable apps platform for electronic health records

J. Am. Medical Informatics Assoc., 2016
Objective In early 2010, Harvard Medical School and Boston Children’s Hospital began an interoperability project with the distinctive goal of developing a platform to enable medical applications to be written once and run unmodified across different ...
Joshua C. Mandel, David A. Kreda, K. Mandl, I. Kohane, R. Ramoni   +4 more
semanticscholar   +1 more source

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
wiley   +1 more source

Linked Data: Evolving the Web into a Global Data Space

Linked Data, 2011
The World Wide Web has enabled the creation of a global information space comprising linked documents. As the Web becomes ever more enmeshed with our daily lives, there is a growing desire for direct access to raw data not currently available on the Web ...
T. Heath, Christian Bizer
semanticscholar   +1 more source

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone, Alessandra Colamatteo, Teresa Micillo, Gianmarco Abbadessa, Silvia Garavelli, Clorinda Fusco, Claudia Russo, Francesco Perna, Federica Garziano, Claudia La Rocca, Maria Mottola, Giorgia Teresa Maniscalco, Simona Bonavita, Antonio Luca Spiezia, Alessia Castiello, Roberta Lanzillo, Vincenzo Brescia Morra, Claudio Procaccini, Paola de Candia, Giuseppe Matarese   +19 more
wiley   +1 more source

From anarchy to good practice: the evolution of standards in archaeological computing [PDF]

, 2009
This paper reviews the importance of standards in archaeological computing and traces their development, and the tensions surrounding their deployment. Three categories of standards are defined: technical, content and metadata standards.
Richards, J.D.
core   +1 more source

X-ENS: Semantic Enrichment of Web Search Results at Real-Time [PDF]

, 2012
While more and more semantic data are published on the Web, an important question is how typical web users can access and exploit this body of knowledge.
Fafalios, Pavlos, Tzitzikas, Yannis
core   +3 more sources

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

A PROPOSAL TO USE SEMANTIC WEB TECHNOLOGIES FOR IMPROVED ROAD NETWORK INFORMATION EXCHANGE [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Data harmonisation improves the coherence between data sets within and across themes and is, therefore, a very helpful tool for governmental agencies, companies and other organisations that share their data.
M. G. Niestroj, D. A. McMeekin, P. Helmholz, M. Kuhn   +3 more
doaj   +1 more source