Results 61 to 70 of about 153,822 (301)
Speeding in Web Surveys: The tendency to answer very fast and its association with straightlining
Survey Research Methods, 2014 Web surveys can be programmed to capture a variety of paradata regarding how respondents answer questions. These paradata provide great opportunities for researchers to assess response quality, specifically whether respondents engage in satisficing – not
Chan Zhang, Frederick Conrad
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Influence of the Design of Web Survey Questionnaires on the Quality of Responses
Survey Research Methods, 2008 he first objective of this article is to propose a conceptual framework of the effects of on-line questionnaire design on the quality of collected responses. Secondly, we present the results of an experiment where different protocols have been tested and
Stéphane Ganassali
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Online surveys-possibilities, pitfalls and practicalities: the experience of the TELA evaluation.
, 2010 Surveys are a commonly used strategy for gaining insights into teacher perspectives. They are often seen as cost effective in terms of time and resources required, but the challenges involved in conducting and processing paper-based surveys can be ...
Harlow, Ann
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Digital Psychological Platform for Mass Web-Surveys
, 2020 Web surveys using digital platforms are one of the popular ways to conduct mass research. However, the intelligent analysis of the answers has a number of features based on the subject area of the conducted surveys. The dataset presents consist from mass
Silaeva, A
core +2 more sources
Drug and Alcohol Dependence Reports, 2022 Introduction:: Updating the mode of data collection may affect response rates or survey results. The ongoing, national Monitoring the Future (MTF) panel study has traditionally used mailed paper surveys.
Megan E. Patrick +4 more
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
The British Geological Survey's New Geomagnetic Data Web Service
Data Science Journal, 2013 Increasing demand within the geomagnetism community for high quality real-time or near-real-time observatory data means there is a requirement for data producers to have a robust and scalable data processing infrastructure capable of delivering ...
E Dawson, J Lowndes, P Reddy
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