Results 41 to 50 of about 454,077 (308)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Partner Market Opportunities and Relationship Stability
Comparative Population Studies, 2015 Although partner market opportunities are generally considered to be important for relationship stability, they have never been measured accurately.
Ingmar Rapp +3 more
doaj
YENİ BİR TOPLUM KURAM DİNAMİĞİ: PRATİK-RASYONELLİK
Afyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2020 Rasyonellik genel bir tabirle günümüzde toplumsal yapının ve alt sistemlerin üzerine kurulu olduğu dinamiklerin oluşturduğu temel varsayımlardan biridir.
Ahmet Yavuz Çamlı
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Frontiers in Human Neuroscience, 2014 Variability of Practice (VOP) refers to the acquisition of a particular target movement by practicing a range of varying targets rather than by focusing on fixed repetitions of the target only.
Marc eBangert +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Weber’s Protestant Ethic Thesis in Five Steps
Academicus International Scientific Journal, 2019 As a result of many years of reading about and teaching Max Weber’s famous Protestant Ethic thesis, I have developed an approach to covering this material in both my undergraduate and graduate theory courses which has been beneficial to students and has ...
James J. Chriss
doaj +1 more source
Max Weber: The Reason of a Dialogue
Scienza & Politica, 2020 The essay identifies and analyses the main similarities between Weber’s and Foucault’s work. They concern the three main areas of their reflection: knowledge, power and the subject. These thematic axes are always firmly intertwined in their work.
Furio Ferraresi
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Der Feldzug des Geheimen Kommerzienraths Stumm gegen das "Neunkircher Tageblatt"
, 1881 wahrheitsgemäss dargestellt von Joh.
Weber, Johann
core +1 more source