Results 221 to 230 of about 3,580,404 (289)

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

open access: yesAdvanced Science, EarlyView.
Fibroblast activation protein alpha‐positive (FAPα+) macrophages, a distinct subset of multiple myeloma (MM)‐associated macrophages, drive immune evasion in MM through multi‐faceted mechanisms. FAPα physically interacts with vimentin (VIM) and triggers its phosphorylation at the S72 residue, which in turn induces PD‐L1 transcription. Additionally, FAPα
Huiyao Gu   +15 more
wiley   +1 more source

Impact of Operating Room Efficiencies on Patient Outcomes Following Primary Coronary Artery Bypass Surgery. [PDF]

open access: yesInterdiscip Cardiovasc Thorac Surg
Patel JA   +21 more
europepmc   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

Utility of <sup>18</sup>F-Flurpiridaz PET Relative Flow Reserve in Differentiating Obstructive From Nonobstructive Coronary Artery Disease. [PDF]

open access: yesCirc Cardiovasc Imaging
Lopez DM   +14 more
europepmc   +1 more source

Enhancing the Ultrasonic Welding of Wood Using 3D Printed Lignin Energy Directors

open access: yesAdvanced Science, EarlyView.
Sustainable manufacturing for lightweight structures using ecofriendly materials will be key to reducing material consumption and lowering carbon footprints. Here, an approach is presented to weld wood using ultrasonic vibrations with material at the joint interface to direct energy.
Muhamad Amani   +6 more
wiley   +1 more source

Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites

open access: yesAdvanced Science, EarlyView.
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev   +8 more
wiley   +1 more source

Ensemble perception of duration and size. [PDF]

open access: yesAtten Percept Psychophys
Bratzke D, Ellinghaus R.
europepmc   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

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