Results 21 to 30 of about 670,585 (273)
Modern weapons and military equipment for issue 4-2020
This paper describes and analyses construction details of the Corner Shot platform, in order to shape its flaws and traits.
Miloš M. Jevtić
doaj
COMMUNICATION TOOLS OF THE INTERNET ENVIRONMENT AS A MODERN MEANS OF BUSINESS PROMOTION
For the successful sale of goods and services in a modern digital society, there is a need to transfer marketing to the Internet environment. The main tools of marketing communications are advertising, PR, sales promotion and direct marketing, each of ...
Aleksandr V. Ponachugin +2 more
doaj +1 more source
This essay deals with The Obscure Cities, a well-known series elaborated by Benoît Peeters and François Schuiten between 1982 and 2019, a period that witnessed the emergence and further institutionalization of digital media.
Jan Baetens
doaj +1 more source
Abstract: CloudBook is a notes-taking platform that allows users to create and organize notes in separate files with headings, subheadings, and content. The platform automatically updates the changes made when users save and sign out. While phone notepads are commonly used to write down grocery lists, to-do lists, or notes from presentations, these ...
Aanchal Padmavat +3 more
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Dünya genelinde insanları etkileyen Covid-19 Salgını bireyin, toplumun doğru bir şekilde bilgilendirilmesi ve yönlendirilmesi açısından iletişimin öneminin daha net bir şekilde anlaşıldığı dönem olarak devam etmektedir.
Burak Çeber, Ahmet Fuat Polat
doaj +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
This image is as example of what not to do when communicating with patients during diagnosis consultation. It was drawn for Christine Phillips of the Australian National University School of Medicine in 2012.
Hugh James Brocklebank, Tanisha Jowsey
doaj +1 more source

