Results 31 to 40 of about 670,585 (273)

Culturally Sensitive Website Elements and Features: A Cross-National Comparison of Websites from Selected Countries

open access: yesActa Informatica Pragensia, 2020
The goal of this case study is to compare websites from 9 different countries|Austria, Chile, China, Japan, Latvia, Nigeria, Saudi Arabia, the US and the Czech Republic|and, based on this comparison, to provide the missing linking of website elements ...
Radim Cermak
doaj   +1 more source

Conceptual characteristics and peculiarities of the implementation of interaction between government institutions and citizens in Ukraine using e-Governance resources

open access: yesЕкономіка, управління та адміністрування, 2023
The development of modern information technologies, which is conceptually implemented in the practice of public administration through the e-Government system, allows using new non-traditional forms of interaction with citizens and effectively promoting ...
G.I. Lyahovych , G.I. Zhekalo
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Preliminary studies of fungi in the Biebrza National Park (NE Poland). I. Micromycetes

open access: yesActa Mycologica, 2013
This paper presents the results of the first short-term inventory of fungi species occurring in the Biebrza National Park, one of the biggest and best preserved protected areas of Poland. The paper is focused on a survey of microfungi.
Małgorzata Ruszkiewicz-Michalska   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The Effectiveness of Using an Interactive e-Module to Improve Learning Outcomes

open access: yesJABE (Journal of Accounting and Business Education), 2023
This research aims to determine the effectiveness of using an interactive e-module based on a website using Google Site for tax-related material. This research phase employs a two-group pretest-posttest with control group research design.
Darpiyah - Darpiyah, Sulastri - Sulastri
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Interprofessional education or silo education?

open access: yesCanadian Medical Education Journal, 2019
Hand drawn and coloured using Adobe Photoshop 2015. This image depicts the difficulties that practitioners have in working in interprofessional teams when they train in separate buildings and don't learn together.
Hugh James Brocklebank, Tanisha Jowsey
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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