Results 41 to 50 of about 670,585 (273)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Informatization programs as a component of the mechanism of e-government implementation: comparative characteristics of cities

Економіка, управління та адміністрування, 2020
Today, the key component of development in the system of public administration is the introduction of elements of e-government at all stages of interaction between government agencies and the public.
G.I. Zhekalo, A.V. Klyuchenko
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

African Mountains in a Changing Climate: Trends, Impacts, and Adaptation Solutions

Mountain Research and Development, 2019
African mountains are home to millions of people and provide a diversity of ecosystem services. Coupled with factors such as population growth and land-use change, climate change is putting more pressure on these mountains, with potential impacts on ...
Philbert Nsengiyumva
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Artificial Intelligence and Voice Modeling: Cutting-edge Technology in Music Production

Studia Universitatis Babeş-Bolyai. Musica
This article reports on some of the benefits that Artificial Intelligence has brought during the renaissance of AI science. It also reveals a few of the shortcomings surrounding it from 2010 until the beginning of 2025. The examples provided reflect our
Adrian BORZA
doaj   +1 more source

Data Logging Implementation on Web-Based Communication on Arduino Devices

JOIN: Jurnal Online Informatika, 2019
Arduino is one of the microcontroller devices commonly used on the Internet of Things. This research designed and objectified web-based data logging system that aimed to record communication and sensir data in iot devices, so it could monitor log data in
Yasyfi Rahmanda Tsani, Alif Subardono
doaj   +1 more source

Rancang Bangun Sistem Kontrol dan Monitoring Data Turbin Angin Berbasis Website Menggunakan Raspberry Pi 3B+

Metal: Jurnal Sistem Mekanik dan Termal, 2020
Indonesia has considerable wind energy potential. Energy generation system performance can be monitored and controlled through the Internet of Things (IoT) technology.
Meiki Eru Putra, Zulkifli Amin, Islahuddin Islahuddin, Sanny Ardhy   +3 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta, Stefano Callegaro, Antonio Canosa, Umberto Manera, Maurizio Grassano, Francesca Palumbo, Sara Cabras, Enrico Matteoni, Francesca Di Pede, Filippo De Mattei, Salvatore Tafaro, Neil M. Thakur, Ryan Grosenick, Fabiola De Marchi, Letizia Mazzini, Cristina Moglia, Andrea Calvo, Kuldip D. Dave, Adriano Chiò   +18 more
wiley   +1 more source