Results 21 to 30 of about 29,236 (264)

A quantitative approach to evaluate usability of academic websites based on human perc

Egyptian Informatics Journal, 2014
In this competitive world, websites are considered to be a key aspect of any organization’s competitiveness. In addition to visual esthetics, usability of a website is a strong determinant for user’s satisfaction and pleasure.
Sharmistha Roy, Prasant Kumar Pattnaik, Rajib Mall   +2 more
doaj   +1 more source

Accessibility and readability of university websites in Finland

Journal of Accessibility and Design for All, 2012
This article describes a study conducted by the authors to evaluate the accessibility and readability of the contents of the Web sites of seven universities in Finland.
Markku Karhu, José R. Hilera, Luis Fernández, Ricardo Ríos   +3 more
doaj   +1 more source

Foot and Ankle Fellowship Websites

Foot & Ankle Orthopaedics, 2016
Category: Other Introduction/Purpose: The Internet has been reported to be the first informational resource for many fellowship applicants. Despite being a popular resource, no accessibility or quality standards exist for fellowship websites.
Natalie R. Danna MD, Richard M. Hinds, John T. Capo, Kenneth J. Mroczek MD   +3 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

How Accessible the University Websites in Indonesia for People with Disabilities?

Indonesian Journal of Disability Studies, 2020
Website in higher education utilized for many purposes such as providing learning resources, information, and news related to student's academic needs.
Fitri Dwi Arini
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Web accessibility investigation and identification of major issues of higher education websites with statistical measures: A case study of college websites

Journal of King Saud University: Computer and Information Sciences, 2022
The World Wide Web Consortium (W3C) has provided the most important set of guidelines for web accessibility which is popularly known as Web Content Accessibility Guidelines (WCAG). The accessibility analysis of higher education websites becomes paramount
Abid Ismail, K.S. Kuppusamy
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source