Results 81 to 90 of about 1,242,519 (279)

Digital Inclusion for Access to Information: A Study on Banking and Financial Institutions in India

open access: yesSAGE Open, 2017
Banking and Financial Institutions (BFIs) show the growth of development of a country. Digital literacy and its development in a country depend on its use by the citizens of a country. In India, they have recently made strides in using digital technology
P. J. Mathew Martin   +1 more
doaj   +1 more source

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Applying the Skip Navigation Links in the Context of the Websites’ Accessibility of Central Public Administration Bodies in the Nitra Region [PDF]

open access: yesSocietas et Iurisprudentia, 2015
The study focuses in its main aim on seeking yet undetected or undefined deficits in relation to applying the skip navigation mechanism on the websites of the central public administration bodies in the Nitra Region in the context of improving the ...
Jana Koprlová
doaj  

Web Accessibility in Higher Education Institutions of Ecuador: Year 2016

open access: yesJournal of Science and Research, 2016
This research was conducted in order to establish the progress made by the web accessibility in the pages of higher education institutions verify ing how many of them implement the NTE INEN ISO/IEC40500standard,which establishes accessibility guidelines ...
Nelly Karina Esparza Cruz   +2 more
doaj   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

open access: yesAdvanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang   +8 more
wiley   +1 more source

Applying the Skip Navigation Links in the Context of the Websites’ Accessibility of Central Public Administration Bodies in the Prešov Region [PDF]

open access: yesSocietas et Iurisprudentia, 2016
The study focuses in its main aim on seeking yet undetected or undefined deficits in relation to applying the skip navigation mechanism on the websites of the central public administration bodies in the Prešov Region in the context of improving the ...
Jana Koprlová
doaj  

An Update on Foot and Ankle Fellowship Website Content and Accessibility

open access: yesFoot & Ankle Orthopaedics, 2020
Background: The content and accessibility of foot and ankle fellowship websites impact applicants and fellowship programs. This study aimed to evaluate the accessibility provided via the American Orthopaedic Foot & Ankle Society (AOFAS) websites and ...
Ansab Khwaja MD   +3 more
doaj   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

open access: yesAdvanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang   +9 more
wiley   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

Accessible Website Content Guidelines for Users with Intellectual Disabilities [PDF]

open access: green, 2007
Joyce Karreman   +2 more
openalex   +1 more source

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