Results 121 to 130 of about 256,079 (316)

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

open access: yesAdvanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Electronic Educational and Research Services as Infrastructure for the E- Government: Role of [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2013
Introduction: Websites serve as an initial step toward an e- government adoption which facilitates delivery of online services to customers. The existing study intended to investigate the role of university website to render educational and research ...
merdad Farzandipour   +2 more
doaj  

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu   +12 more
wiley   +1 more source

Websites of Note [PDF]

open access: yesInterface magazine, 2010
openaire   +1 more source

Project Website

open access: yes, 2019
This document is deliverable “D6.1 Project Website”, which presents the functionality of the official website of the EO4AGRI project. More specifically the document describes the portal website and the implemented features available for the public. The web portal, which can be publicly accessed at the url address www.eo4agri.eu , has been launched on ...
openaire   +1 more source

Website Preferences of Finnish and Mexican University Students: A Cross-Cultural Study

open access: yesSeminar.net, 2015
This paper is focused on understanding Internet use and comparingcross-cultural differencesaccording tothe contents and preferences of the websites that are most visited bytwogroupsof university students from Finland (n=30) and Mexico (n=30).The ...
Miguel Santiago, Pirkko Hyvönen
doaj  

Accessibility Issues in Ad-Driven Web Applications [PDF]

open access: yesarXiv
Website accessibility is essential for inclusiveness and regulatory compliance. Although third-party advertisements (ads) are a vital revenue source for free web services, they introduce significant accessibility challenges. Leasing a website\'s space to ad-serving technologies like DoubleClick results in developers losing control over ad content ...
arxiv  

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Intelligent Usability Evaluation for Fashion Websites [PDF]

open access: yesarXiv
Websites have become increasingly important in people's lives, fulfilling a wide range of needs across various domains such as shopping, education, news, and booking. Among the most heavily used website categories are online shopping platforms, whose usage has particularly increased during the COVID-19 pandemic, as they eliminate time and geographical ...
arxiv  

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

open access: yesAdvanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su   +17 more
wiley   +1 more source

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