Results 151 to 160 of about 287,450 (302)

Academic & Special Library Websites in Bangalore City An Evaluative Study

open access: yes, 2012
The academic & special library websites are mirror of their collection, services and user-focused gateways to rich, quality content and they play a key role in the learning and research processes.
Konnur, P.V., Mohan, T.A., Rajani, S.
core  

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

open access: yesAdvanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li   +14 more
wiley   +1 more source

Archiving and Long Term Preservation of Websites and Born Digital Documents in Slovakia

open access: yes, 2019
Presentation for the 2019 International Internet Preservation Consortium General Assembly and Web Archiving Conference.
Hausleitner, Peter   +2 more
core  

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo   +14 more
wiley   +1 more source

The Form Of Websites: Studying The Formal Development Of Websites, The Case Of Professional Danish Football Clubs 1996-2021 [Presentation]

open access: yes
This presentation discusses how we can analyze the historical development of the form of websites based on the holdings in web archives. In other words: what can we say about a website's form, no matter which concrete words, images, graphics, videos and ...
Brügger, Niels
core  

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

open access: yesAdvanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du   +9 more
wiley   +1 more source

Análisis del color en los websites de productos sobre flamenco.

open access: yes, 2014
El flamenco se ha convertido en los últimos años en un nicho de mercado en alza, tanto en España como fuera de ella. Teniendo en cuenta esto y la ya demostrada importancia del comercio electrónico, proliferan en Internet los sitios webs donde se venden ...
Mª Antonia Hurtado Guapo   +1 more
core  

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

open access: yesAdvanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

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