Results 211 to 220 of about 1,023,650 (323)

YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li   +8 more
wiley   +1 more source

Websites of Note [PDF]

open access: bronze, 2000
Graham R. Parslow
openalex   +1 more source

Website

open access: yes
Delivarable 5.1 involves applications in comminications and open access in order to publicate widely within dissemination and exploitation activities. To provide these activities the structure and the design of the Bio-Acouis web site which is already launched as online and available.
openaire   +2 more sources

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

open access: yesAdvanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo   +14 more
wiley   +1 more source

Spine Surgery Fellowships in Mexico: Web Content and Accessibility. [PDF]

open access: yesInt J Spine Surg
Aguilar-Chavez F   +6 more
europepmc   +1 more source

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

open access: yesAdvanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu   +12 more
wiley   +1 more source

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