Results 1 to 10 of about 417,611 (276)

Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia [PDF]

open access: yesFrontiers in Pharmacology
IntroductionRadiation-induced thrombocytopenia (RIT) is a serious complication of cancer radiotherapy, for which therapeutic options are limited. This study investigates wedelolactone (WED), a metabolite of a botanical drug, as a potential treatment for ...
Zhichao Li   +13 more
doaj   +2 more sources

Trauma writing reduces conserved transcriptional response to adversity (CTRA) gene expression: A culturally adapted pilot study [PDF]

open access: yesComprehensive Psychoneuroendocrinology
Introduction: Psychosocial interventions to reduce posttraumatic stress disorder (PTSD)-associated distress can improve health of people with PTSD. To identify potential biological mechanisms, we tested whether a PTSD-focused written emotional disclosure
Gail Ironson   +6 more
doaj   +2 more sources

AcrIIA19 binds to the WED domain and inhibits various Cas9 orthologs at multiple stages [PDF]

open access: yesCommunications Biology
Anti-CRISPR (Acr) proteins are natural inhibitors of clustered regularly interspaced short palindromic repeat (CRISPR)–CRISPR-associated protein (Cas) systems, providing valuable tools for regulating genome editing. Here, we present the crystal structure
Gi Eob Kim   +4 more
doaj   +2 more sources

Development and psychometric validation of the women’s empowerment in dealing with intimate partner violence (WED-IPV) scale: a mixed-method study [PDF]

open access: yesBMJ Open
Objectives The present study aimed to develop and psychometrically validate a culturally sensitive instrument, the women’s empowerment in dealing with intimate partner violence (WED-IPV) scale, in Iran.Design A mixed-methods research study to collect and
Mohtasham Ghaffari   +2 more
doaj   +2 more sources

Depression and Sleep Quality in Restless Legs Syndrome/Willis-Ekbom Disease

open access: yesBoğaziçi Tıp Dergisi, 2023
INTRODUCTION: Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is a well-known neurological sensory motor disorder. As a result of sleep fragmentation, quality of life has effected and incidence of anxiety and depression increase.
Ceyhun Sayman   +2 more
doaj   +1 more source

Silver-zinc redox-coupled electroceutical wound dressing disrupts bacterial biofilm. [PDF]

open access: yesPLoS ONE, 2015
Pseudomonas aeruginosa biofilm is commonly associated with chronic wound infection. A FDA approved wireless electroceutical dressing (WED), which in the presence of conductive wound exudate gets activated to generate electric field (0.3-0.9V), was ...
Jaideep Banerjee   +9 more
doaj   +1 more source

UPLC-QTOF-MS-based lipidomic study of wedelolactone in acute colitis mice induced by dextran sulfate sodium

open access: yesHeliyon, 2023
Inflammatory bowel disease is a relapsing inflammatory disease seriously endanger human health. Wedelolactone (WED) is a major active ingredient from Eclipta prostrata (L.) L. and has shown anti-inflammatory effects.
Yuanyuan Gou   +7 more
doaj   +1 more source

Technical Delivery Parameters of 2000 Proton Treatment Courses [PDF]

open access: yesInternational Journal of Particle Therapy, 2020
Purpose: To summarize the technical delivery parameters of proton plans delivered at the Mayo Clinic in Rochester, Minnesota. Materials and Methods: The database of treated patient proton plans was queried to extract field parameters such as gantry angle,
Amanda J. Deisher   +5 more
doaj   +1 more source

Windowed Eigen-Decomposition Algorithm for Motion Artifact Reduction in Optical Coherence Tomography-Based Angiography

open access: yesApplied Sciences, 2022
Optical coherence tomography-based angiography (OCTA) has attracted attention in clinical applications as a non-invasive and high-resolution imaging modality. Motion artifacts are the most seen artifact in OCTA.
Tianyu Zhang   +8 more
doaj   +1 more source

Wedelolactone ameliorates synovial inflammation and cardiac complications in a murine model of collagen-induced arthritis by inhibiting NF-κB/NLRP3 inflammasome activation

open access: yesFolia Histochemica et Cytobiologica, 2022
INTRODUCTION: Rheumatoid arthritis (RA) is an autoimmune disorder associated with joint damage and attendant cardiovascular complications. Wedelolactone (Wed), derived from Eclipta alba, possesses anti-inflammatory activity.
Jingjing Cao   +3 more
doaj   +1 more source

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