Results 51 to 60 of about 28,105 (306)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

The implications of LinkedIn medium and Weibull-based probability model in the financial sector

Alexandria Engineering Journal
In today's modern world, marketing is a fruitful source to grow a business by reaching a larger audience. This paper considers a popular social media source called LinkedIn.com as a way of marketing or reaching a larger audience. We consider a regression
Ze Li, Weihong Zhou, Fatimah A. Almulhim, Jin-Taek Seong, Manahil Sid Ahmed Mustafa, Hassan M. Aljohani   +5 more
doaj   +1 more source

Some Theoretical and Computational Aspects of the Inverse Generalized Power Weibull Distribution [PDF]

, 2021
Mahmoud Ali Selim
openalex   +1 more source

A New Paradigm for Understanding the Rheology and Processability of Poly(p‐Phenylene Terephthalamide) Liquid‐Crystalline Solutions

Journal of Applied Polymer Science, EarlyView.
Kevlar is traditionally modeled as a rigid‐rod polymer, yet rheological behavior deviates from this assumption. The review introduces a novel “twist‐tie” entanglement theory for aramid polymer chains in the nematic liquid crystal state, providing a molecular explanation for deviations from rigid‐rod models. Understanding twist‐tie entanglement dynamics
Emma Egli, Jacob L. Pretko, Christopher W. Seay, Steven R. Lustig   +3 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Exponentiated Transmuted Weibull Distribution A Generalization Of The Weibull Distribution

, 2014
This paper introduces a new generalization of the two parameter Weibull distribution. To this end, the quadratic rank transmutation map has been used. This new distribution is named exponentiated transmuted Weibull (ETW) distribution. The ETW distribution has the advantage of being capable of modeling various shapes of aging and failure criteria ...
openaire   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli, Sakib Ferdous, J. Michael Hess, Nigel F. Reuel   +3 more
wiley   +1 more source

A new trigonometric-inspired probability distribution: A simulation study and applications in reliability and hydrology

Alexandria Engineering Journal
The importance of statistical distributions in accurately representing real-world scenarios and aiding in educated decision-making is well recognized. Nonetheless, it is also true that the limitations of these distributions can hinder optimal fitting in ...
Xiang Tu, Jiangwei Kong, Qing Fu, Sheng Chang, Kunfeng Zhang, Tmader Alballa, Haifa Alqahtani, Hamiden Abd El-Wahed Khalifa   +7 more
doaj   +1 more source

Topp-Leone Weibull Generated Family of Distributions with Applications [PDF]

, 2022
Ibrahim A. Elbatal, Tamer S. Helal, Ahmed M. Elsehetry, Rasha S. Elshaarawy   +3 more
openalex   +1 more source

Effect of confining pressure on fracture characteristics and mineralogical behavior of tight sandstone specimens after hydraulic fracturing

Deep Underground Science and Engineering, EarlyView.
Hydraulic fracturing in tight sandstone and fracture propagation characteristics using backscattered electron‐scanning electron microscope (BSE‐SEM) images. Abstract This study focuses on hydraulic fracturing experiments conducted under triaxial conditions on tight sandstone specimens from Shivpuri district, Madhya Pradesh, India.
Pankaj Rawat, Narendra Kumar Samadhiya
wiley   +1 more source