Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT The FDA has mandated a Boxed Warning for glatiramer acetate (GA) due to the risk of serious anaphylactic reaction. This study aimed to characterize the reported features of GA‐associated anaphylaxis. Data mining was performed using the Reporting Odds Ratio (ROR) in the FDA Adverse Event Reporting System (FAERS) database (Q1 2004–Q1 2025) and ...
Tailei Nie +4 more
wiley +1 more source
Discrimination performance in illness-death models with interval-censored disease data. [PDF]
Stat Methods Med ResSpreafico M +3 more
europepmc +1 more source
Sex‐Related Differences in Physiologically‐Based Biopharmaceutics Modeling
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.Sex‐related differences in gastrointestinal tract physiology and their incorporation into three widely used PBPK platforms (PK‐Sim, GastroPlus, Simcyp) were evaluated. A ketoprofen PBPK model was developed and verified in males, then extrapolated to females using default and sex‐specific refined parameters, demonstrating that user‐defined adjustments ...
Marianela Chavarría‐Rojas +4 more
wiley +1 more source
A New Parametric Accelerated Failure Time Model for Semi-Competing Risks Data. [PDF]
Stat MedDineva A, Kuss O, Hoyer A.
europepmc +1 more source
Engaging with theoretical models in social science education
Review of Education, Volume 14, Issue 2, August 2026.Abstract In citizenship education, subjects like social science aim to enhance students' reasoning about social issues through disciplinary knowledge, skills and abilities. One key ability is using theories and models to better understand and reason about societal phenomena.
Johan Sandahl, Patrik Johansson
wiley +1 more source
Bayesian and non-bayesian approaches for estimating the Epanechnikov-Weibull distribution with applications in engineering and electronics data. [PDF]
Sci RepTaher TS +4 more
europepmc +1 more source
Statistical Analysis and Data Mining: An ASA Data Science Journal, Volume 19, Issue 4, August 2026.ABSTRACT Conformity of observed data with a postulated probability distribution is a fundamental problem of statistical modeling. Current tools for checking distributional conformity are often limited to univariate settings, with extensions to multivariate distributions facing challenges in interpretability and power.
Rasha Alsaadawi, Nitai D. Mukhopadhyay
wiley +1 more source
Inventory optimization under tri phased demand with dual aging and controlled backlogging. [PDF]
iScienceArunadevi E, Umamaheswari S.
europepmc +1 more source
A Bayesian Optimal Adaptive Clinical Trial Design for Sequentially Integrated Therapies
Statistics in Medicine, Volume 45, Issue 18-19, August 2026.ABSTRACT Clinical syndromes or diseases with complex etiology often require multiple treatments, each addressing one specific aspect of the disease. Such treatments are typically administered sequentially in an integrated fashion. For example, in alcohol‐associated hepatitis (AH), an acute liver disease caused by excessive alcohol drinking, successful ...
Yining Li +5 more
wiley +1 more source
A Bayesian Prevalence-Incidence Mixture Model for Screening Outcomes With Misclassification. [PDF]
Stat MedKlausch T +2 more
europepmc +1 more source