Results 181 to 190 of about 122,077 (293)

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang   +5 more
wiley   +1 more source

Waist‐to‐Height Ratio and the Risk of Cardiovascular Outcomes and Mortality in Type 2 Diabetes With and Without Abdominal Obesity

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Waist‐to‐height ratio (WHtR) has been suggested as a superior marker of cardiometabolic risk compared to waist circumference (WC), but evidence in type 2 diabetes mellitus (T2DM) remains limited. Materials and Methods A population‐based cohort of 2 076 104 patients with T2DM who underwent the Korean national health checkup between 2015 and
Kye‐Yeung Park   +7 more
wiley   +1 more source

Polygenic Risk Score Predicts Prostate Cancer Risk Independent of Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Type 2 diabetes mellitus (T2DM) has been inversely associated with prostate cancer (PrCa) risk. However, it remains unclear whether a polygenic risk score (PRS) for PrCa can effectively stratify risk among men with T2DM. The primary objective of this study was to assess whether a PrCa PRS predicts PrCa risk independently of T2DM status ...
Guk Jin Lee   +32 more
wiley   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li   +9 more
wiley   +1 more source

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