Results 41 to 50 of about 122,379 (272)

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality

Hepatology, EarlyView., 2022
Visualisation of the study desgin, main results and key findings. Abstract Background and Aims MAFLD often cooccurs with excessive alcohol consumption, while its prognostic value in this group remains unclear. We aimed to study the mortality risk of MAFLD in relation to excessive alcohol consumption and its potential interactions.
Laurens A. van Kleef, Robert J. de Knegt, Willem Pieter Brouwer   +2 more
wiley   +1 more source

A Toolkit to assess health needs for congenital disorders in low- and middle-income countries: an instrument for public health action. [PDF]

, 2013
BACKGROUND: In 2010 the World Health Assembly called for action to improve the care and prevention of congenital disorders, noting that technical guidance would be required for this task, especially in low- and middle-income countries. Responding to this
Alberg, C, Burton, H, Chowdhury, S, Darlison, MW, Grollman, C, Hall, A, Modell, B, Moorthie, S, Nacul, LC, Sagoo, GS, Stewart, A   +10 more
core   +3 more sources

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Ethnic specific obesity cut-offs for diabetes risk: cross-sectional study of 490, 288 UK Biobank participants [PDF]

, 2014
OBJECTIVE To compare the relationship between adiposity and prevalent diabetes across ethnic groups in the UK Biobank cohort and to derive ethnic-specific obesity cutoffs that equate to those developed in white populations in terms of diabetes prevalence.
Gill, Jason, Mackay, Daniel, Ntuk, Uduakobong, Pell, Jill, Sattar, Naveed   +4 more
core   +1 more source

Incidence of components of metabolic syndrome in the metabolically healthy obese over 9 years follow-up: the Atherosclerosis Risk In Communities study. [PDF]

, 2017
BackgroundSome obese adults are not afflicted by the metabolic abnormalities often associated with obesity (the 'metabolically healthy obese' (MHO)); however, they may be at increased risk of developing cardiometabolic abnormalities in the future. Little
Bradshaw, PT, Ndumele, CE, Reynolds, KR, Stevens, J, Wagenknecht, LE   +4 more
core   +2 more sources

Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. [PDF]

, 2014
OBJECTIVES: To examine associations between sarcopenia, obesity, and sarcopenic obesity and risk of cardiovascular disease (CVD) and all-cause mortality in older men. DESIGN: Prospective cohort study.
Atkins, JL, Lennon, LT, Morris, RW, Papacosta, O, Wannamethee, SG, Whincup, PH   +5 more
core   +1 more source

The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white European descent [PDF]

, 2018
Aims: The data regarding the associations of body mass index (BMI) with cardiovascular (CVD) risk, especially for those at the low categories of BMI, are conflicting. The aim of our study was to examine the associations of body composition (assessed by
Anderson, Jana, Celis-Morales, Carlos A., Gill, Jason M.R., Gray, Stuart R., Iliodromiti, Stamatina, Lyall, Donald M., Mackay, Daniel F., Nelson, Scott M., Pell, Jill P., Sattar, Naveed, Welsh, Paul   +10 more
core   +1 more source

Associations between weight-adjusted-waist index and infertility: Results from NHANES 2013 to 2020

Medicine, 2023
Female infertility is a significant problem for women of reproductive age worldwide. Obesity has been proven to pose a danger for infertility in women. Weight-adjusted waist circumference index (WWI) is a recently created biomarker of obesity, and this research aims to explore the relationship between female infertility and WWI.
Huanxin Zhong, Bin Yu, Fen Zhao, Hongyin Cui, Lifang You, Dao Feng, Yi Lu   +6 more
openaire   +2 more sources

Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants [PDF]

, 2017
Background - Obesity is a multifactorial condition influenced by genetics, lifestyle and environment. Objective - To investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) with body mass index (BMI)
Bailey, Mark E.S., Biello, Stephany M., Celis-Morales, Carlos, Gill, Jason M.R., Guo, Yibing, Llamas, Daniel, Lyall, Donald M., Mackay, Daniel F., Pell, Jill P., Steell, Lewis, Ward, Joey   +10 more
core   +1 more source