Results 131 to 140 of about 13,390,811 (365)

Weight Control System [PDF]

open access: yes, 1969
Weight Control System, a set of linked computer programs which provides weight and balance reports from magnetic tape files, provides weight control and reporting on launch vehicle programs.
Dyer, A., Jr.   +2 more
core   +1 more source

The effect of strain rate on macrozones of the α+β phase region during thermal deformation in near-α titanium alloys

open access: yesJournal of Materials Research and Technology
The homogenous microstructure of near-a titanium alloys is important to service in complex and dynamic environments. However, macrozones characterized by sharp local textures are common microstructural inhomogeneities in titanium (Ti) alloys, which ...
Xiaolei Wang   +8 more
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Less weight more fun [PDF]

open access: yes, 2000
Microlight Aviation is still in its infancy, yet in the 20 years since enthusiasts around the world started fitting lawnmower engines to hang-gliders or small makeshift wings progress has been remarkable.
Gratton, GB
core  

BASAL METABOLISM AND IDEAL WEIGHT AND PULSE RATIOS [PDF]

open access: green, 1922
Anne Peterson, WILL WALTER
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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