Results 131 to 140 of about 5,958,077 (318)
Journal of Eating DisordersIn a thought-provoking opinion piece written largely from his own lived experience, James Downs calls for a ‘re-imagination’ and broadening of the concepts, principles and practices of early intervention and prevention of eating disorders (EDs), to ...
Ulrike Schmidt +3 more
doaj +1 more source
Portrait of Michael Johnson, 1988 [picture] /
, 1988 Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/15/R.; Also available in electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of Eating DisordersBackground Eating disorders (EDs) are serious illnesses which profoundly impact individuals and the people close to them. Despite robust evidence that early intervention improves clinical outcomes, help-seeking by individuals with EDs is low and long ...
Jessica Wilkins +3 more
doaj +1 more source
Portrait of Geoff de Groen, 2001 [picture] /
, 2001 Title supplied by vendor.; Part of collection: Portraits of six Australian artists.
Weight, Greg, 1946-
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Portrait of Alun Leach-Jones, 1991 [picture] /
, 1991 Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/27/R.; Also available online at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Portrait of Margaret Woodward, 1992 [picture] /
, 1992 Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/23/R.; Also available online at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source