Results 161 to 170 of about 3,690,704 (199)

Fruit weight regulation by a paralog of Cell Size Regulator (CSR) in tomato and other crops. [PDF]

Theor Appl Genet
Feng Q, Pereira L, Sapkota M, Karnatam KS, Wang Y, Nimmakayala P, Reddy UK, van der Knaap E.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

ARD-101, a gut-restricted TAS2R agonist, reduces hunger in adults and promotes weight loss in DIO mice with DPP-4 inhibition. [PDF]

Mol Metab
Zheng Z, Pettus JH, Warner A, Jones B, Pugsley M, Stege J, Hirakawa B, Jaiman M, Tolentino J, Lee TL, Kieffer TJ.   +10 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Perceptions of Obesity and Weight-Related Behaviors Among Adults With Type 2 Diabetes in Benin. [PDF]

J Nutr Educ Behav
Alaofè H, Okechukwu A, Magrath P, Girard C, Hounkpatin WA, Ehiri J.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Drug‐Coated Balloons in In‐Stent Restenosis, a New Standard of Care or Yesterday's News?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Nicholas Weight, Mamas A. Mamas
doaj   +1 more source

Added Technology for Weight Management in Cardiac Rehabilitation: Biopsychosocial Factors and Rehabilitees' Talk in a Mixed Method Study.

J Med Internet Res
Lahtio H, Paajanen T, Korpi H, Heinonen A, Sjögren T.   +4 more
europepmc   +1 more source

Moderate weight loss decreases lipedema-affected body fat mass in a woman who is lean with lipedema. [PDF]

JCEM Case Rep
De Girolamo G, Smith GI, Stein RI, Wright TF, Klein S.   +4 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source