Results 181 to 190 of about 13,390,811 (365)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Probing deformation mechanisms of CoCrFeNiMn0.75Cu0.25 highentropy alloy after thermo-mechanical treatment using in situ EBSD investigation

Journal of Materials Research and Technology
In this study, the CoCrFeNiMn0.75Cu0.25 high-entropy alloy (HEA) was systematically investigated to elucidate the effects of different annealing temperatures on the microstructure and mechanical properties of the face-centered cubic (fcc) structural ...
Wujing Fu, Jingwei Ren, Guohua Fan, Xuewen Li, Yongjiang Huang   +4 more
doaj  

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Autobiographical memory and episodic future thinking in anorexia nervosa: a three-year follow-up

Journal of Eating Disorders
Background People with anorexia nervosa (AN) show deficiencies with recalling specific details of autobiographical memories (AM). This may interfere with wider processes of self-narrative construction and identity building, which are a fundamental part ...
Johanna Louise Keeler, Valentina Cardi, Georgia Peters-Gill, Hubertus Himmerich, Kate Tchanturia, Janet Treasure   +5 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

The Ravages, Life History, Weights of Stages, Natural Enemies and Methods of Control of the Melon Fly (Dacus Cucurbitae Coq.) [PDF]

, 1914
Henry H. P. Severin, H. C. Severin, William J. Hartung   +2 more
openalex   +1 more source

Maternal weight gain and birth weight

Journal of the Chinese Medical Association, 2021
Huann-Cheng Horng, Peng-Hui Wang, Wen-Ling Lee   +2 more
openaire   +3 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

THE EFFECT OF ADMINISTRATION OF SMALL AMOUNTS OF THYROID GLAND ON THE SIZE AND WEIGHT OF CERTAIN ORGANS IN THE MALE WHITE RAT [PDF]

, 1920
James Arthur Hewitt
openalex   +1 more source