Results 41 to 50 of about 3,690,704 (199)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Exploring successes, barriers, and enablers in the one-year digital Healthy Weight Coaching

open access: yesBMC Health Services Research
Introduction Healthcare professionals’ perspectives are often overlooked in the evaluation of digital weight loss interventions. Thus, we examined how healthcare professionals perceive patient success in a one-year web-based weight management program ...
Anu Joki   +3 more
doaj   +1 more source

Defeating strength-plasticity trade-off of Al–Zn–Mg–Cu alloy by spray forming and double step extrusion

open access: yesJournal of Materials Research and Technology
A well strength-plasticity balance is necessary for industry application of high Zn 7xxx series alloys. Herein, we proposed a combination process of spray forming rapid solidification plus extrusion processes (i.e., single forward extrusion (FE alloy ...
Kaiyun Xiang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Endoscopic removal of a weight-loss device with stoma closure using a tack-and-suture device

open access: yesVideoGIE, 2023
Areebah Waseem, BS   +5 more
doaj   +1 more source

Microstructure and Mechanical Properties of Ultrafine-Grained Dual-Phase 0.1C3Mn Steel Processed by Warm Deformation

open access: yesMetals
In this study, we have explored the thermomechanical processing on 0.1C3Mn steel to produce an ultrafine-grained (UFG) dual-phase (DP) microstructure. The composition was designed to allow a decrease in temperature for the warm deformation of austenite ...
Yongkang Wang, Chenglu Liu, Qingquan Lai
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Preclinical obesity curriculum: audit, implementation, and evaluation

open access: yesBMC Medical Education
Background This study aimed to (1) evaluate the current status of obesity education at Case Western Reserve University School of Medicine (CWRU) (2), introduce a comprehensive first-year curriculum on obesity, and (3) assess the impact of the curriculum ...
Amber Olson   +5 more
doaj   +1 more source

The Patient’s Journey in Obesity within the United States: An Exercise of Resilience against Disease

open access: yesLife
Obesity is often viewed as a result of patient failure to adhere to healthy dietary intake and physical activity; however, this belief undermines the complexity of obesity as a disease.
Kayla Northam   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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