Results 101 to 110 of about 3,529,038 (262)

Obesity‐Related Beliefs, Concerns, and Stigmatizing Perceptions Among Adults Living With Obesity

open access: yesObesity Science & Practice
Background Weight stigma represents a barrier to effective obesity management and to achieving health equity. Although most research has focused on high‐income countries, data from Latin America remain scarce.
Luiz F. Viola   +10 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Tracey Moffatt, 1995 [1] [picture] /

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an21108595 ...
Weight, Greg, 1946-
core  

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Body shaming and internalized weight bias as potential precursors of eating disorders in adolescents

open access: yesFrontiers in Psychology
IntroductionBody shaming (BS) is a growing phenomenon within the school context, especially among adolescents. Recently, it has been described as an unrepeated act in which a person expresses unsolicited, mostly negative comments about an individual’s ...
Silvia Cerolini   +4 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Portrait of Margaret Olley, 1991 [picture] /

open access: yes, 1991
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference prints at P641/1/R.; Also available in electronic version via the Internet at: http://nla.gov.au/nla.pic-an12119221; Exhibited: In the ...
Weight, Greg, 1946-
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Portrait of Wendy Stavrianos, 2001 [picture] /

open access: yes, 2001
Title supplied by vendor.; Part of collection: Portraits of six Australian artists. Portrait taken at the Gaspard Studios, formerly an old shearing shed, Walmer, Victoria, 20 March 2001.--Photographer's ...
Weight, Greg, 1946-
core  

Home - About - Disclaimer - Privacy