Results 91 to 100 of about 4,022,212 (305)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study

Frontiers in Cellular and Infection Microbiology
IntroductionExcessive body weight was associated with changes in individual microbiota. However, limited research on the impact of excessive gestational weight gain (GWG) revealed that microbiota patterns related to GWG differed from those linked to ...
Katarzyna Kosinska-Kaczynska, Magdalena Zgliczynska, Dominika Krawczyk, Magdalena Piatkowska, Aneta Balabas, Paweł Czarnowski, Krzysztof Goryca, Krzysztof Goryca, Piotr Glinicki, Piotr Glinicki, Jerzy Ostrowski, Jerzy Ostrowski, Natalia Zeber-Lubecka, Natalia Zeber-Lubecka   +13 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Estimation of a Dynamic Model of Weight [PDF]

The ongoing debate about the economic causes of obesity has focused on the changing relative prices of diet and exercise. This paper uses a model that explicitly includes time and spatially varying community-level urbanicity and price measures as ...
Edward C. Norton, Barry M. Popkin, David K. Guilkey, Shu Wen Ng   +3 more
core  

Factors Associated with Interdialytic Weight Gain and Its Percentage: Are 2 Metrics Interchangeable?

Turkish Journal of Nephrology
Background: Interdialytic weight gain (IDWG) is a key indicator of fluid management in hemodialysis patients. Greater IDWG reflects nonadherence to fluid restriction, excessive salt intake, and has been associated with reduced quality of life, increased
Duc Manh Nguyen
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of gestational weight gain in women with twin pregnancies and its relationship to neonatal birth weight. A pilot study

Background To date, there have been no studies in Poland on weight gain in women with twin pregnancies in relation to recommendations. Objective The aim of this study was to analyze the gestational weight gain of women with twin pregnancies depending on
Regina Wierzejska
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Overweight and obesity pose a big challenge to pregnancy as they are associated with adverse maternal and perinatal outcome. Evidence of lifestyle intervention resulting in improved pregnancy outcome is conflicting.
Croker, H, Varma, Rajesh, Oteng-Ntim, Eugene, Poston, Lucilla, Helen Croker, Poston, L, Doyle, P, Lucilla Poston, Rajesh Varma, Oteng-Ntim, E, Varma, R, Croker, Helen, Doyle, Pat, Eugene Oteng-Ntim, Pat Doyle, Poston, Lucilla; id_orcid   +15 more
core   +2 more sources