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Inverse agonism gains weight

Trends in Pharmacological Sciences, 2003
Inverse agonism is emerging as a new endogenous principle for receptor regulation. Agouti-related protein (AgRP), following its release in the brain, stimulates food intake. AgRP binds to brain melanocortin receptors, which are involved in the regulation of body weight.
Roger A H, Adan, Martien J H, Kas
openaire   +2 more sources

Ziprasidone and Weight Gain

Clinical Neuropharmacology, 2004
We describe the case of a 12-year-old white male in whom significant weight gain occurred within 3 months of treatment with Ziprasidone. It is important that clinicians are aware of this possibility since this medication is marketed as one of the few antipsychotic medications not associated with significant weight gain.
Sol, Jaworowski   +3 more
openaire   +2 more sources

Drug-induced weight gain

Drugs of Today, 2005
Drug-induced weight gain is a serious side effect of many commonly used drugs leading to noncompliance with therapy and to exacerbation of comorbid conditions related to obesity. Improved glycemic control achieved by insulin, insulin secretagogues or thiazolidinedione therapy is generally accompanied by weight gain.
Rosane, Ness-Abramof   +1 more
openaire   +3 more sources

Antidepressants and weight gain

Appetite, 1988
Weight gain is an often reported, but incompletely understood, side effect of many antidepressant medications. We will discuss the literature with respect to the following issues: weight gain as a pharmacological effect of antidepressants or as an effect of recovery from depression; the incidence of antidepressant-induced weight gain and possible ...
M J, Russ, S H, Ackerman
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Lithium and Weight Gain

International Clinical Psychopharmacology, 1990
Lithium prophylaxis leads to weight gain in a high proportion of patients treated, with up to a quarter becoming clinically obese. This can have detrimental effects on compliance and is also a health risk. The mechanism of such lithium-induced weight gain is unknown, but increased calorie intake, particularly in the form of high calorie drinks, has ...
Y, Chen, T, Silverstone
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Weight Gain in Pregnancy

Journal of Obstetric, Gynecologic & Neonatal Nursing, 1986
The amount of weight that women are advised to gain during pregnancy has changed significantly in the past few decades. In the past, recommendations were aimed at curtailing weight gain because of problems surrounding delivery (i.e., cephalopelvic disproportion or toxemia).
K R, Dohrmann, S A, Lederman
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Drug-induced Weight Gain

Drugs, 1980
Untoward long term morbidity and mortality and excess non-compliance with treatment may result from the weight gain induced by some drugs used for the treatment of severe psychological disorder. Whilst some weight gain during the recovery from psychological disorder is to be expected, excess weight gain, over and above the patients normal weight, is ...
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Hysterectomy and weight gain

Menopause, 2009
To investigate whether overweight women are more likely to have a hysterectomy and whether hysterectomy leads to increased weight gain.Survey data of middle-aged women participating in the Australian Longitudinal Study on Women's health in 1996 (ages 45-50 y; n = 13,125), 1998 (n = 10,612), 2001 (n = 10,293), and 2004 (n = 9309) included self-reported ...
Fitzgerald, DM   +3 more
openaire   +3 more sources

Counseling About Weight Gain Guidelines and Subsequent Gestational Weight Gain

Journal of Women's Health, 2015
The purpose of this study was to investigate what percentage of postpartum women were informed about how much weight to gain during pregnancy, the accuracy of the weight gain recommendations based on the 2009 Institute of Medicine (IOM) gestational weight gain (GWG) recommendations and whether being informed was associated with greater likelihood of ...
Brian H, Wrotniak   +5 more
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Weight Gain

Journal of Clinical Psychopharmacology, 1999
During clinical experience with the "atypical" neuroleptic drugs clozapine, risperidone, and zotepine, some patients have shown a marked weight gain. To prove whether weight gain is a relevant side effect of atypical neuroleptics, the charts of all patients admitted with DSM-III-R diagnoses of schizophrenia, schizoaffective disorder, or delusional ...
T, Wetterling, H E, Müssigbrodt
openaire   +2 more sources

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