Results 91 to 100 of about 1,908,958 (312)

The weight-inclusive vs. weight-normative approach to health: Evaluating the evidence for prioritizing well-being over weight [PDF]

, 2014
Using an ethical lens, this review evaluates two methods of working within patient care and public health: the weight-normative approach (emphasis on weight and weight loss when defining health and well-being) and the weight-inclusive approach (emphasis ...
Shuman, E., Chad Davis, Deb Burgard, Annunziato, R.A., Tracy L. Tylka, Tylka, Tracy L., Danielsdottir, S., Rachel A. Annunziato, Davis, C., Sigrún Daníelsdóttir, Burgard, D., Rachel M. Calogero, Calogero, Rachel M., Ellen Shuman   +13 more
core   +1 more source

Weight loss [PDF]

Postgraduate Medical Journal, 1996
D, Scullion, A, Al-Kutoubi
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assessing the effect of weight and weight loss in obese persons with type 2 diabetes [PDF]

, 2008
Bradley Curtis1, Risa P Hayes1, Sheri Fehnel2, Laurie Zografos21Global Health Outcomes, Eli Lilly and Co, Indianapolis, IN, USA; 2RTI Health Solutions, Research Triangle Park, NC, USAAbstract: The objective of this study was to assess specific areas of ...
Risa P Hayes, Bradley Curtis, Sheri Fehnel, Laurie Zografos   +3 more
core  

Metabolic and behavioral compensations in response to caloric restriction: Implications for the maintenance of weight loss [PDF]

, 2009
BackgroundMetabolic and behavioral adaptations to caloric restriction (CR) in free-living conditions have not yet been objectively measured.Methodology and principal findingsForty-eight (36.8+/-1.0 y), overweight (BMI 27.8+/-0.7 kg/m(2)) participants ...
Eric Ravussin, Ravussin, E., Corby K. Martin, Leanne M Redman, Heilbronn, L., Corby K Martin, James P. Delany, Lilian de Jonge, Leonie K Heilbronn, Donald A Williamson, James P Delany, de Jonge, L., DeLany, J., Redman, L., Leanne M. Redman, null null, Martin, C., Pennington CALERIE Team, Williamson, D., Leonie K. Heilbronn, Donald A. Williamson   +20 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Contour Deformities After Massive Weight Loss [PDF]

, 2012
Popularity of bariatric surgery has increased exponentially over the past several years. As a result, a new patient's population has emerged seeking plastic surgery: the Massive Weight Loss (MWL) patient.
Rueda, Steven, Rebane, Mari, Thaller, Seth   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Latent profiles of nurses’ attitudes toward artificial intelligence in nursing and associated factors: a cross-sectional study

BMC Nursing
Background Artificial intelligence (AI) is being gradually integrated into clinical nursing practice, where it plays an important role in improving nursing quality, reducing nurses’ workload, and promoting the intelligent transformation of nursing ...
Tingting Wei, Ting Wang, Jiaojiao Ruan, Xueying Pang, Peng Zhou, Zhengyiqing Wang, Mingxia Hu, Shanshan Chen, Xiumei Zhang, Chengcong Li   +9 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source