Results 61 to 70 of about 8,342,732 (338)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Feasibility and Impact of a Combined Supervised Exercise and Nutritional-Behavioral Intervention following Bariatric Surgery: A Pilot Study

Journal of Obesity, 2015
Background. Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the feasibility and impact of an 8-week combined supervised exercise with nutritional-behavioral ...
Friedrich C. Jassil, Sean Manning, Neville Lewis, Siri Steinmo, Helen Kingett, Fiona Lough, Andrea B. F. Pucci, W. H. Cheung, Nicholas Finer, Judith Walker, Jaqueline Doyle, Rachel L. Batterham   +11 more
doaj   +1 more source

Determinants of weight loss maintenance: a systematic review

Obesity Reviews, 2018
Discerning the determinants of weight loss maintenance is important in the planning of future interventions and policies regarding overweight and obesity.
R. D. M. Varkevisser, M. M. Stralen, W. Kroeze, J. Ket, I. H. Steenhuis   +4 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Effect of tea consumption on the development of hypertension, diabetes, and obesity: a bidirectional two-sample Mendelian randomization analysis

Frontiers in Nutrition
BackgroundThe effect of tea consumption on conditions such as hypertension, diabetes, and obesity has attracted significant global interest. However, the results of various studies on this topic have been mixed and somewhat contentious.
Xueying Li, Xueying Li, Congcong Zhang, Congcong Zhang, Congcong Zhang, Yihui Weng, Yihui Weng, Weiming Yu, Weiming Yu, Xianlei Cai, Xianlei Cai   +10 more
doaj   +1 more source

Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.

Journal of the American Medical Association (JAMA), 2016
IMPORTANCE Five medications have been approved for the management of obesity, but data on comparative effectiveness are limited. OBJECTIVE To compare weight loss and adverse events among drug treatments for obesity using a systematic review and network
Rohan Khera, M. Murad, A. Chandar, P. Dulai, Zhen Wang, L. Prokop, R. Loomba, M. Camilleri, Siddharth Singh   +8 more
semanticscholar   +1 more source

Weight Loss

Definitions, 2020
When considering weight loss, consider the possibility of an error in recorded weights.Obtain a thorough dietary history. Consider inaccuracy, especially if an eating disorder is possible.A basic workup should be performed before attributing the loss ...

semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Perspectives into the experience of successful, substantial long-term weight-loss maintenance: a systematic review

International Journal of Qualitative Studies on Health & Well-Being, 2021
Purpose: In light of the increasing prevalence of overweight and obesity, understanding the experiences, strategies and challenges encountered when trying to achieve substantial, sustainable weight loss is an important area to investigate.
Marie Spreckley, Jaap Seidell, Jutka Halberstadt   +2 more
doaj   +1 more source

Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents.

New England Journal of Medicine, 2016
BACKGROUND Bariatric surgery is increasingly considered for the treatment of adolescents with severe obesity, but few prospective adolescent-specific studies examining the efficacy and safety of weight-loss surgery are available to support clinical ...
T. Inge, A. Courcoulas, T. Jenkins, M. Michalsky, M. Helmrath, M. Brandt, C. Harmon, M. Zeller, Mike K. Chen, S. Xanthakos, M. Horlick, C. Buncher   +11 more
semanticscholar   +1 more source