Results 111 to 120 of about 10,444,260 (254)

Suspected Mitochondrial Dysfunction and Complex Pathophysiology in Fatal Hypermobile Ehlers–Danlos Syndrome: Insights from a Case Report and Post-Mortem Findings

Biomedicines
Background/Objectives: Hypermobile Ehlers–Danlos Syndrome (hEDS) is a complex connective tissue disorder with multi-systemic manifestations that significantly impact quality of life.
Arash Shirvani, Purusha Shirvani, Ugochukwu Jonah, Brian E. Moore, Michael F. Holick   +4 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Switching the focus from weight to health: Canada's adult obesity practice guideline set a new standard for obesity management

EClinicalMedicine, 2021
Rachel L. Batterham
doaj   +1 more source

Feasibility and Preliminary Effects of Community-Based High-Intensity Functional Training for Adults with Mobility Disabilities and Overweight/Obesity: A Pilot Study

Sports
Background: Preliminary evidence supports high-intensity functional training (HIFT) for improving various health outcomes in non-disabled adults with overweight/obesity.
Lyndsie M. Koon, Joseph E. Donnelly, Joseph R. Sherman, Anna M. Rice, Julianne G. Clina, John Thyfault, Reed Handlery, Kaci Handlery, Derek A. Crawford   +8 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Portrait of Justin O'Brien, 1993 [picture] /

, 1993
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/18/R.; Also available online at: http://nla.gov.au/nla.pic-an12090944; Exhibited: "Sublime", The Gallery, National Library of ...
Weight, Greg, 1946-
core  

Weight management interventions for pregnant women from minority ethnic populations living in the United Kingdom: a scoping review [PDF]

Baraa Morsy, Britzer Paul Vincent, Sarmad Raza, Bhavneet Singh, Nasreen Ali   +4 more
openalex   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Portrait of John Bell, 1968 [picture] /

, 1968
Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/22/R.; Also available online at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
core