Results 61 to 70 of about 10,444,260 (254)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Long Jack Phillipus Tjakamarra, Northern Territory, 2007 [picture] /
, 2007 Title devised by cataloguer based on inscriptions.; Part of the collection: Portraits of prominent indigenous artists of the Western Desert region of the Northern Territory, 2007.; Inscriptions: Photographer's blind stamp lower right corner; "A/P Long ...
Weight, Greg, 1946-
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Judy Napangardi Watson, Yuendumu, Northern Territory, 2007 [picture] /
, 2007 Title devised by cataloguer based on inscriptions.; Part of the collection: Portraits of prominent indigenous artists of the Western Desert region of the Northern Territory, 2007.; Inscriptions: "A/P GW"--In ink below image; Photographer's blind stamp ...
Weight, Greg, 1946-
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Ronnie Tjampitjinpa, Alice Springs, Northern Territory, 2007 [picture] /
, 2007 Title devised by cataloguer based on inscriptions.; Part of the collection: Portraits of prominent indigenous artists of the Western Desert region of the Northern Territory, 2007.; Inscriptions: "A/P GW"--In ink below image; Photographer's blind stamp ...
Weight, Greg, 1946-
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Betsy Napangardi Lewis, Yuendumu, Northern Territory, 2007 [picture] /
, 2007 Title devised by cataloguer based on inscriptions and acquisitions documentation.; Part of the collection: Portraits of prominent indigenous artists of the Western Desert region of the Northern Territory, 2007.; Inscriptions: "A/P GW"--In ink below image;
Weight, Greg, 1946-
core
Journal of Obesity, 2011 It is unclear whether ethnic differences exist in adipose tissue (AT) and skeletal muscle (SM) distribution in black and white youth. Investigation into the pattern of AT and SM distribution in black versus white youth may provide insight into the ...
SoJung Lee +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source