Results 261 to 270 of about 842,589 (329)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

open access: yesAdvanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li   +22 more
wiley   +1 more source

On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy

open access: yesAdvanced Science, EarlyView.
An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Spatial interactions modulate tumor growth and immune infiltration. [PDF]

open access: yesNPJ Syst Biol Appl
Marzban S   +9 more
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

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