Results 71 to 80 of about 647,893 (263)
Budownictwo o Zoptymalizowanym Potencjale EnergetycznymMining exploitation of hard coal occurs in the Silesian region of Poland, resulting in the formation of post-mining voids that cause uneven lowering of the ground level. Consequently, thousands of buildings are tilted from vertical.
Krzysztof Gromysz +3 more
doaj +1 more source
Decision making with Dempster-Shafer belief structure and the OWAWA operator
Technological and Economic Development of Economy, 2014 A new decision making model that uses the weighted average and the ordered weighted averaging (OWA) operator in the Dempster-Shafer belief structure is presented.
José M. Merigo +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MetrologyMany fields or disciplines (e.g., uncertainty analysis in measurement science) require a combination of probability distributions. This technical note examines three methods for combining probability distributions: weighted linear pooling, geometric ...
Hening Huang
doaj +1 more source
Average distance in weighted graphs
Discrete Mathematics, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Hierarchical forecasting of COVID-19 cases in Africa using machine learning models
Frontiers in EpidemiologyIntroductionThe COVID-19 pandemic posed significant challenges for public health systems, especially in Africa, where data scarcity, inadequate healthcare infrastructure, and regional disparities hindered effective forecasting and response efforts ...
Claris Shoko +2 more
doaj +1 more source