Results 41 to 50 of about 11,193 (264)

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On a Sum of More Complex Product-Type Operators from Bloch-Type Spaces to the Weighted-Type Spaces

open access: yesAxioms, 2023
The aim of the present paper is to completely characterize the boundedness and compactness of a sum operator defined by some more complex products of composition, multiplication, and mth iterated radial derivative operators from Bloch-type spaces to ...
Cheng-Shi Huang, Zhi-Jie Jiang
doaj   +1 more source

Weighted Composition Operators on Quasi-Banach Weighted Sequence Spaces

open access: yesSiberian Mathematical Journal, 2023
В работе рассматриваются основные топологические свойства операторов весовой композиции на весовых пространствах последовательностей $l^p(\text{w})$, $0<p<\infty,$ где $\text{w}$ - весовая последовательность положительных чисел: ограниченность, компактность, компактность разностей операторов, формулы для их существенных норм, а также описание тех
A. V. Abanin, R. S. Mannanikov
openaire   +2 more sources

Li–Yorke chaotic weighted composition operators

open access: yesRevista de la Real Academia de Ciencias Exactas, Físicas y Naturales. Serie A. Matemáticas
We establish complete characterizations of the notion of Li-Yorke chaos for weighted composition operators on $C_0(X)$ spaces and on $L^p(μ)$ spaces. As a consequence, we obtain simple characterizations of the Li-Yorke chaotic weighted shifts on $c_0$ and on $\ell^p$ ($1 \leq p < \infty$) that complement previously known results. We also investigate
Nilson C. Bernardes   +1 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Weighted Composition Operators from Generalized Weighted Bergman Spaces to Weighted-Type Spaces

open access: yesJournal of Inequalities and Applications, 2009
Let φ be a holomorphic self-map and let ψ be a holomorphic function on the unit ball B. The boundedness and compactness of the weighted composition operator ψCφ from the generalized weighted Bergman space into a class of ...
Dinggui Gu
doaj   +1 more source

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