Tight Paths and Tight Pairs in Weighted Directed Graphs
We state the graph-theoretic computational problem of finding tight paths in a directed, edge-weighted graph, as well as its simplification of finding tight pairs. These problems are motivated by the need of algorithms that find so-called basic antecedents in closure spaces, in one specific approach to data analysis.
openaire +2 more sources
Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang +13 more
wiley +1 more source
Evolutionary Kuramoto dynamics unravels origins of chimera states in neural populations. [PDF]
Zdyrski T, Pauls S, Fu F.
europepmc +1 more source
Charge Generation and Recombination Pathways in All‐Polymer Bulk Heterojunction Solar Cells
Multimodal spectroscopy and device analysis reveal how field‐dependent charge generation, transport limitations, and non‐geminate recombination govern performance losses in all polymer solar cells. The results identify the key processes controlling charge extraction and recombination, providing insights for the design of more efficient all‐polymer ...
Shahidul Alam +17 more
wiley +1 more source
Multimodal Branched Transport Infers Anatomically Aligned Brain Reaction Maps. [PDF]
Mendico C.
europepmc +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Blurred magnitude homology of functional connectome for ASD diagnosis. [PDF]
Kachura A +3 more
europepmc +1 more source
A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang +16 more
wiley +1 more source
TransPilot: mining key transcription factors by correlating binding sites with differentially expressed genes. [PDF]
Tinghua H +7 more
europepmc +1 more source
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka +2 more
wiley +1 more source

