Results 41 to 50 of about 279,833 (216)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Picture Fuzzy Weighted Distance Measures and their Application to Investment Selection [PDF]

Amfiteatru Economic, 2019
The picture fuzzy set (PFS) is a powerful tool to collect and handle large amounts of uncertain assess information in a new light. In this study, we explore some distance measures for the PFSs and propose Picture fuzzy ordered weighted distance measure
Meiling Liu, Shouzhen Zeng, Tomas Baležentis , Dalia Streimikiene   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Climatic Droughts Zoning Using Inverse Distance Weighted Method

تحقيقات جغرافيايی, 2016
Drought is one of inevitable climatically and harmful characteristics of Iran. Therefore the research and study of this phenomenon will be very necessary.
Mohammad Ali Hakim Zadeh, Motahareh Esfandiari   +1 more
doaj  

Adaptive Distance-Weighted Voronoi Tessellation for Remote Sensing Image Segmentation

Remote Sensing, 2020
The spatial fragmentation of high-resolution remote sensing images makes the segmentation algorithm put forward a strong demand for noise immunity. However, the stronger the noise immunity, the more serious the loss of detailed information, which easily ...
Xiaoli Li, Jinsong Chen, Longlong Zhao, Shanxin Guo, Luyi Sun, Xuemei Zhao   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Weighted evidence combination method based on power-Pignistic probability distance

Tongxin xuebao, 2018
To deal with the shortcomings encountered when using the existing similarity/dissimilarity measures to quantify evidence conflict,a new dissimilarity measure called power-Pignistic probability distance was defined.Furthermore,a weighted evidence ...
Jingwei ZHU, Xiaodan WANG, Yafei SONG, Wenlong HUANG   +3 more
doaj   +2 more sources

A FAST METHOD FOR MEASURING THE SIMILARITY BETWEEN 3D MODEL AND 3D POINT CLOUD [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
This paper proposes a fast method for measuring the partial Similarity between 3D Model and 3D point Cloud (SimMC). It is crucial to measure SimMC for many point cloud-related applications such as 3D object retrieval and inverse procedural modelling. In
Z. Zhang, J. Li, J. Li, X. Li, Y. Lin, S. Zhang, S. Zhang, C. Wang   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source