Results 81 to 90 of about 1,199,843 (260)

A weighted and distributed algorithm for multi-hop localization

International Journal of Distributed Sensor Networks, 2019
Multi-hop wireless sensor networks are widely used in many location-dependent applications. Most applications assume the knowledge of geographic location of sensor nodes; however, in practical scenarios, the high accuracy on position estimates of sensor ...
Juan Cota-Ruiz, Rafael Gonzalez-Landaeta, Jose David Diaz-Roman, Boris Mederos-Madrazo, Ernesto Sifuentes   +4 more
doaj   +1 more source

Weighted estimates for solutions of the $\partial$ -equation for lineally convex domains of finite type and applications to weighted bergman projections

, 2016
In this paper we obtain sharp weighted estimates for solutions of the $\partial$-equation in a lineally convex domains of finite type. Precisely we obtain estimates in spaces of the form L p ({\Omega},$\delta$ $\gamma$), $\delta$ being the distance to ...
Charpentier, Philippe, Dupain, Y, Mounkaila, M   +2 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Jackknifing Weighted Least Squares Estimators

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1989
SUMMARY In a heteroscedastic linear regression model, the ordinary jackknife estimator of the asymptotic covariance matrix of the weighted least squares estimator is proved to be inconsistent. A modified jackknife procedure is proposed and shown to produce consistent estimators of the asymptotic covariance matrix.
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Corrigendum to "Weighted $L^p$ estimates for the elliptic Schrödinger operator" [Electron. J. Qual. Theory Differ. Equ. 2014, No. 33, 1-13]

Electronic Journal of Qualitative Theory of Differential Equations, 2015
An error in Lemma 1.5 in "Weighted $L^p$ estimates for the elliptic Schrödinger operator" [Electron. J. Qual. Theory Differ. Equ. 33(2014) 1-13] is corrected.
Fengping Yao
doaj   +1 more source

Estimates for Fourier sums and eigenvalues of integral operators via multipliers on the sphere

, 2014
We provide estimates for weighted Fourier sums of integrable functions defined on the sphere when the weights originate from a multiplier operator acting on the space where the function belongs. That implies refined estimates for weighted Fourier sums of
Jordão, Thaís, Menegatto, Valdir A.
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source