Results 51 to 60 of about 3,168,234 (244)
Battlefield assembly location algorithm based on single step weighted least squares
Aiming at the problem that fast,high-precision and low-cost positioning is difficult to meet in typical non-cooperative areas,such as the battlefield assembly of airborne troops,a single-step weighted least squares algorithm was proposed based on the ...
Yuchao ZHAO, Hongtuo YUAN, Ming SUN
doaj
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Overview of total least squares methods
We review the development and extensions of the classical total least squares method and describe algorithms for its generalization to weighted and structured approximation problems.
Markovsky, Ivan, Van Huffel, Sabine
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Numerical simulation is a powerful technique for slope stability assessment and landslide hazard investigation. However, the physicomechanical parameters of the simulation results are susceptible to uncertainty.
Wujiao Dai, Yue Dai, Jiawei Xie
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Recent advances in total least squares approaches for solving various errors-in-variables modeling problems are reviewed, with emphasis on the following generalizations: 1.
Markovsky, Ivan +2 more
core +1 more source
Weighted Least Squares Regression with the Best Robustness and High Computability
A novel regression method is introduced and studied. The procedure weights squared residuals based on their magnitude. Unlike the classic least squares which treats every squared residual as equally important, the new procedure exponentially down-weights
Yijun Zuo, Hanwen Zuo
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source

