Results 121 to 130 of about 2,169,038 (282)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
An EigenFactor-weighted power mean generalization of the Euclidean Index.
PLoS ONE, 2019 This paper proposes a weighted generalization of the recently developed Euclidean Index. The weighting mechanism is designed to reflect the reputation of the journal within which an article appears.
M Ryan Haley
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Logarithmic mean and weighted sum of geometric and anti-harmonic means
Journal of Numerical Analysis and Approximation Theory, 2012 We consider the problem of finding the optimal values \(\alpha,\ \beta\in\mathbb{R}\) for which the inequality\[\alpha G(a,b)+(1-\alpha)C(a,b)
Mira Cristiana Anisiu, Valeriu Anisiu
doaj +2 more sources
Factors for Absolute Weighted Arithmetic Mean Summability of Infinite Series
International Journal of Analysis and Applications, 2017 In this paper, we proved a general theorem dealing with absolute weighted arithmetic mean summability factors of infinite series under weaker conditions. We have also obtained some known results.
Hüseyin Bor
doaj +2 more sources
Developing a strategy based on weighted mean of vectors (INFO) optimizer for optimal power flow considering uncertainty of renewable energy generation. [PDF]
Neural Comput Appl, 2023 Farhat M +4 more
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Adaptation strategy of karst forests: Evidence from the community-weighted mean of plant functional traits. [PDF]
Ecol Evol, 2022 Liu L, Hu J, Chen X, Xu X, Yang Y, Ni J.
europepmc +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source