Results 151 to 160 of about 1,301,558 (327)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Certain Polynomials with Weighted Sums

open access: yesJournal of the Chosun Natural Science, 2015
AbstractIn this note, we provide some examples of polynomials z n −p(z), where , and , a k ≥ 0 for eachk such that p(z) has all its zeros on |z|=c 1, and wedenote C(r) by the circle of radius r with center the ori-gin. It follows from Enestrm-Kakeya theorem [1] (see p.136 of [1] for the statement and its proof) to(1)where , a k ≥ 0 for each k that all
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Sum and Weighted Sum Formulas for Fibonacci and Lucas Quaternions

open access: yesAksaray University Journal of Science and Engineering
Fibonacci and Lucas quaternions are deeply studied in the literature after its definition by Horadam in 1963. Binet formula, generation function, Cassini, Catalan, Honsberger, and other identities for these sequences studied in different quaternion algebra types like split quaternion algebra, dual quaternion algebra, etc.
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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