Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Path Analysis With Mixed-Scale Variables: Categorical ML, Least Squares, and Bayesian Estimations. [PDF]
Liang X, Castro P, Cao C, Lo WJ.
europepmc +1 more source
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha +12 more
wiley +1 more source
Spatial patterns and determinants of knowledge on prevention of mother-to-child transmission of HIV in Ethiopia: a geographically weighted regression analysis. [PDF]
Asnake AA +9 more
europepmc +1 more source
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba +18 more
wiley +1 more source
Neuroimaging and Transcriptomic Insights Into Iron Accumulation and Glymphatic Dysfunction in Olfactory Dysfunction. [PDF]
Leong C +10 more
europepmc +1 more source
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli +15 more
wiley +1 more source
User acceptability profiles of vaginal treatments among women with genitourinary syndrome of menopause. [PDF]
Hassanein M +2 more
europepmc +1 more source
Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt +7 more
wiley +1 more source
Identification of Glioma Phenotypic Subtypes From Multimodal MRI Data Using Hierarchical Multi-Kernel Learning. [PDF]
Yan J +9 more
europepmc +1 more source

