Results 91 to 100 of about 17,802 (285)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Some observations during weightlessness sim- ulation with subject immersed in a rotating water tank [PDF]

open access: yes
Observations during weightlessness simulation with subject immersed in rotating water ...
Letko, W., Stone, R. W., Jr.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Corrigendum: Editorial: Rising stars in environmental, aviation and space physiology: 2022

open access: yesFrontiers in Physiology, 2023
Alina Saveko   +6 more
doaj   +1 more source

Laboratory simulation of the action of weightlessness on the human organism [PDF]

open access: yes
A brief history of attemps by the U.S. and the U.S.S.R. to simulate weightlessness in the laboratory is presented. Model for laboratory modeling of weightlessness included the bed regimen, the clinostat, and water immersion.
Genin, A. M.
core   +1 more source

Space flight research relevant to health, physical education, and recreation: With particular reference to Skylab's life science experiments [PDF]

open access: yes, 1979
Data collected in the Skylab program relating to physiological stresses is presented. Included are routine blood measures used in clinical medicine as research type endocrine analyses to investigate the metabolic/endocrine responses to weightlessness ...
Heusner, W. W., Vanhuss, W. D.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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