Results 211 to 220 of about 25,035 (360)
The effect of changing gravity and weightlessness on vasopressin control systems Progress report, 21 Oct. 1969 - 15 Feb. 1970 [PDF]
Changing gravity and weightlessness effects on vasopressin control systems, with immunochemical and biological assay ...
Moran, W. H., Jr.
core +1 more source
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
Investigating the effect of zinc supplementation on preventing bone resorption in a weightlessness animal model: An experimental study [PDF]
Background and aims: Bone biomarkers, such as bone-specific alkaline phosphatase (BAP) and osteocalcin (OC), are crucial for researching and monitoring the effects of therapeutic interventions.
Reza Eslami+2 more
doaj
The Development of the Vestibular Apparatus Under Conditions of Weightlessness [PDF]
A series of experiments has been carried out on the effect of space flight conditions on morphogenesis and the structure of the vestibular apparatus in amphibian and fish larvae.
Gazenko, O. G.+3 more
core +1 more source
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
Computer simulation of preflight blood volume reduction as a countermeasure to fluid shifts in space flight [PDF]
Fluid shifts in weightlessness may cause a central volume expansion, activating reflexes to reduce the blood volume. Computer simulation was used to test the hypothesis that preadaptation of the blood volume prior to exposure to weightlessness could ...
Charles, J. B.+2 more
core +1 more source
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley +1 more source
Maintenance and strengthening of human body musculoskeletal system in weightless environment
Tsuyoshi Ito+2 more
openalex +2 more sources