Results 211 to 220 of about 20,184 (348)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Hemodynamic and Neurohumoral Responses to Simulated Weightlessness and KAATSU Blood Flow Restriction

, 2008
Toshiaki Nakajima, Haruko Iida, Miwa Kurano, Tomohiro Yasuda, Haruhito Takano, Toshihiro Morita, Kentaro Meguro, Yoshiaki Sato, Takashi Abe, Naokata Ishii, Hiroshi Ohshima, Hiroshi Ohshima   +11 more
openalex   +1 more source

Motion sickness susceptibility under weightless and hypergravity conditions generated by parabolic flight [PDF]

Motion sickness susceptibility under weightless and hypergravity conditions generated by parabolic ...
Graybiel, A., Kellogg, R. S., Miller, E. F., II, Odonnell, R. D.   +3 more
core   +1 more source

Role of muscle spindle in weightlessness-induced amyotrophia and muscle pain

, 2009
Umar Ali, Xiaoli Fan, Hao‐Jun You
openalex   +2 more sources

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation. [PDF]

Stem Cell Res Ther
Chang M, Liu R, Chen B, Xu J, Wang W, Ji Y, Gao Z, Liu B, Yao X, Sun H, Xu F, Shen Y.   +11 more
europepmc   +1 more source

Mechanical Factors and Bone Health: Effects of Weightlessness and Neurologic Injury

, 2010
Shreyasee Amin
openalex   +2 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Atom interferometry in an Einstein Elevator. [PDF]

Nat Commun
Pelluet C, Arguel R, Rabault M, Jarlaud V, Métayer C, Barrett B, Bouyer P, Battelier B.   +7 more
europepmc   +1 more source