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The Effects of Simulated Weightlessness on Bone Maturation*
Endocrinology, 1987In earlier studies we showed that elevating the hind limbs of growing rats for up to 2 weeks results in a temporary cessation of bone growth in the hind limbs and a transient fall in the serum levels of 1,25-dihydroxyvitamin D. To determine whether such skeletal unloading also retards the maturation of bone, as seen in vitamin D-deprived animals, we ...
Daniel D. Bikle +4 more
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An upper arm model for simulated weightlessness
Acta Physiologica Scandinavica, 2000This investigation examined the effects of 4 weeks of non‐dominant arm unloading on the functional and structural characteristics of the triceps brachii muscle of six normo‐active college‐age males (age: 23 ± 1 years, height: 176 ± 4 cm, weight: 76 ± 6 kg).
David L. Costill +5 more
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Research advance in effects of weightlessness or simulated weightlessness on tumor cells.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2012Weightless environment is a rare phenomenon on the ground where the interactions among cells and internal cellular structures disappear or become weakened. Studies on the biological features and molecular expression of tumors cells in weightlessness condition may provide new clues to the tumor initiation, process, diagnosis, and therapy.
Yinghua Guo, Changting Liu, De Chang
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Acta Astronautica, 1988
The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified.
Colleen D. Lynch +5 more
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The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified.
Colleen D. Lynch +5 more
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Study of Temperature Homeostasis in Real and Simulated Weightlessness
Human Physiology, 2002The analysis of the temperature (T) reaction of the body of healthy humans was carried out using the results of investigations with the thermometry technique under antiorthostatic hypokinesia (ANOH) (38 males in the studies of 14- to 49-day duration, eight females, 120 days), isolation in a regenerated gas environment (six males, 90 to 135 days), suit ...
I. M. Larina, N. G. Lakota
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Evaluation of the three-dimensional clinostat as a simulator of weightlessness
Planta, 1997Concerns regarding the reliability of slow-and fast-rotating uni-axial clinostats in simulating weightlessness have induced the construction of devices considered to simulate weightlessness more adequately. A new three-dimensional (3-D) clinostat equipped with two rotation axes placed at right angles has been constructed. In the clinostat, the rotation
Seiichiro Kamisaka +4 more
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Changes of brain response induced by simulated weightlessness
Acta Astronautica, 1992The characteristics change of brain response was studied during 15 degrees head-down tilt (HDT) comparing with 45 degrees head-up tilt (HUT). The brain responses evaluated included the EEG power spectra change at rest and during mental arithmetic, and the event-related potentials (ERPs) of somatosensory, selective attention and mental arithmetic ...
Zhiqiang Guan, Jinhe Wei, Gongdong Yan
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Effects of simulated weightlessness on rat osteocalcin and bone calcium [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1989 Some of the musculoskeletal changes that occur in growing rats during spaceflight are simulated by a model that selectively unloads the hindlimbs while maintaining normal weight bearing on the forelimbs. Using this model we studied the response of mineral and the mineral-binding protein osteocalcin (OC) in the third lumbar vertebra (L3) and the ...
Emily Morey-Holton +4 more
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Simulated weightlessness for the ontogenesis of the otolith organ
Die Naturwissenschaften, 1968Abstract : The critical phase of the otolith-organ-ripening within the embryo was used in a simulation experiment by setting frog eggs (Rana temporaria) and toad eggs (Bufo bufo) near the center of a rotating system with a horizontal axis. The experiment speeds were 100 and 160 r.p.m.; the eggs and tadpoles were subjected to maximal centripetal forces ...
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Effects of muscle electrostimulation during simulated weightlessness
Acta Astronautica, 1975In a 45-day experiment test subjects were exposed to bed rest with their heads down at -4 degrees C. Twice a day their muscles of the stomach, back, femur, and shin were stimulated with electric current for 25-30 min. The value of muscle tension was close to their maximum voluntary contraction.
L.I. Kakurin +3 more
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