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Simulated Weightlessness Perturbs the Intestinal Metabolomic Profile of Rats
Frontiers in Physiology, 2019 Recently, disorders of intestinal homeostasis in the space environment have been extensively demonstrated. Accumulating evidence have suggested microgravity and simulated weightlessness could induce dysbiosis of intestinal microbiota, which may contribute to the bowel symptoms during spaceflight. However, the specific responses of intestinal metabolome
Ke Zhao
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A SURVEY OF CHRONIC WEIGHTLESSNESS SIMULATION IN BIOLOGICAL RESEARCH [PDF]
, 1964 Abstract : The central emphasis of the survey concerns the status of research involving various methods of effecting chronic weightlessness for organisms. Three general types of approach are considered: (1) accelerations that oppose the Earth's gravity, (2) indirect reduction of gravitational effects, and (3) indirect information from increases of ...
Charles C. Wunder
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, 1986 The phenomenon of gravitation is characterized by the mutual attraction of any two bodies. The universal character of gravitation was first recognized by Isaac Newton who found the well-known law for the attraction force F acting between two mass points or homogeneous spherical bodies $$\rm F\, = \,\gamma Mm/R^2 $$ (3.1) M, m are the masses ...
H. Hamacher
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Exercise response to simulated weightlessness
Acta Astronautica, 1979Two bed rest analog studies of space flight were performed; one 14 d and the other 28 d in duration. Exercise response was studied in detail during the 28 d study and following both the 14 d and 28 d studies. This paper relates the results of these studies to physiologic changes noted during and following space flight.
J. A. Rummel, M. C. Buderer, C. F. Sawin
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The Effects of Simulated Weightlessness on Bone Maturation*
Endocrinology, 1987In earlier studies we showed that elevating the hind limbs of growing rats for up to 2 weeks results in a temporary cessation of bone growth in the hind limbs and a transient fall in the serum levels of 1,25-dihydroxyvitamin D. To determine whether such skeletal unloading also retards the maturation of bone, as seen in vitamin D-deprived animals, we ...
Daniel D. Bikle +4 more
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An upper arm model for simulated weightlessness
Acta Physiologica Scandinavica, 2000This investigation examined the effects of 4 weeks of non‐dominant arm unloading on the functional and structural characteristics of the triceps brachii muscle of six normo‐active college‐age males (age: 23 ± 1 years, height: 176 ± 4 cm, weight: 76 ± 6 kg).
David L. Costill +5 more
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Acta Astronautica, 1988
The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified.
Colleen D. Lynch +5 more
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The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified.
Colleen D. Lynch +5 more
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Research advance in effects of weightlessness or simulated weightlessness on tumor cells.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2012Weightless environment is a rare phenomenon on the ground where the interactions among cells and internal cellular structures disappear or become weakened. Studies on the biological features and molecular expression of tumors cells in weightlessness condition may provide new clues to the tumor initiation, process, diagnosis, and therapy.
Yinghua Guo, Changting Liu, De Chang
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Responses of Intestinal Mucosal Barrier Functions of Rats to Simulated Weightlessness [PDF]
Frontiers in Physiology, 2018 Exposure to microgravity or weightlessness leads to various adaptive and pathophysiological alterations in digestive structures and physiology. The current study was carried out to investigate responses of intestinal mucosal barrier functions to simulated weightlessness, by using the hindlimb unloading rats model.
Mingliang Jin, Ke Zhao, Chunlan Xu
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Weightlessness or Weightlessness Simulation and Vascular Remodeling
Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2003 Weightlessness is inavoidable during spaceflight. It brings profound physiological effects on human body. Vascular remodeling is one of the important changes of cardiovascular system caused by weightlessness or simulated weightlessness. The paper summarized the studies on the effects of weightlessness or weightlessness simulation on vascular remodeling
Yao Yong
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