Results 91 to 100 of about 1,087,142 (318)
Аnnotation. The article deals with issues related to the development of scientific and methodical positions on the ranking of markets of industrial enterprise. Particular attention is paid to the development of economic and mathematical models to justify
S. Logvinov
doaj
Multicriteria decision‐making (MCDM) methods are used in many areas of human activities. Each alternative in a multicriteria decision‐making problem can be described by a set of criteria. Criteria can be qualitative and quantitative.
Edmundas Kazimieras Zavadskas +1 more
doaj +1 more source
Cages ($r$-regular graphs of girth $g$ and minimum order) and their variants have been studied for over seventy years. Here we propose a new variant, "weighted cages". We characterize their existence; for cases $g=3,4$ we determine their order; we give Moore-like bounds and present some computational results.
Gabriela Araujo-Pardo +3 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BODY WEIGHT AND ORGAN WEIGHT IN RATS
To define the standard for the normal physiological status of rats, about 300 Wistar strain rats, bred in our department, were examined for body weight gain with age in day, and weight of 11 organs-hypophysis, thyroid, adrenal, thymus, testis, ovary, uterus, heart, liver, spleen and kidney-were obtained for each body weight group.
Tadokoro, Sakutaro +4 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
rwightman/pytorch-image-models: MaxxVit (CoAtNet, MaxVit, and related experimental weights)
CoAtNet (https://arxiv.org/abs/2106.04803) and MaxVit (https://arxiv.org/abs/2204.01697) timm trained weights Weights were created reproducing the paper architectures and exploring timm sepcific additions such as ConvNeXt blocks, parallel partitioning ...
Yuki Tatsunami +29 more
core +1 more source
Weight distribution of the crown-weight space
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dae San Kim, Sung Hee Cho
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

