Results 81 to 90 of about 137,245 (308)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

PB2116: CLINICAL PRESENTATION AND TREATMENT OUTCOME OF CHILDREN WITH B-CELL LYMPHOMA; 3-YEAR STUDY AT CHILDREN’S WELFARE TEACHING HOSPITAL (2016-2018)

HemaSphere, 2022
H. Ghali, M. Al-Jadiry, R. Haitham, A. Fadhil, R. Majid, S. Faraj, A. Hatem, S. Abdulrazzaq, S. Al-Hadad   +8 more
doaj   +1 more source

Resting-state functional connectivity involved in tactile orientation processing

NeuroImage
Background: Grating orientation discrimination (GOD) is commonly used to assess somatosensory spatial processing. It allows discrimination between parallel and orthogonal orientations of tactile stimuli applied to the fingertip.
Ryoki Sasaki, Sho Kojima, Kei Saito, Naofumi Otsuru, Hiroshi Shirozu, Hideaki Onishi   +5 more
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Residents’ perception of duty hour limits through teaching hospital accreditation status—experience in Taiwan

Journal of the Formosan Medical Association, 2017
Residents’ work overload is a rising issue in Taiwan. Duty hours of the residents in the United States have been limited by the Accreditation Council for Graduate Medical Education Common Program Requirements since 2003; similar standards were not ...
Tsung-Hsi Wang, Brian C. Drolet, Kun-Yu Tsai, Yu-Fu Liu   +3 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

General Welfare Reporter [PDF]

, 1946
Monthly newspaper from Oklahoma City, Oklahoma published in the interest of the Oklahoma Division General Welfare Federation of America that includes news pertinent to welfare rights and the welfare rights ...
Finley, Ira M.
core   +6 more sources

PB2301: PEDIATRIC IMMUNE THROMBOCYTOPENIA; A GLANCE AT PATIENTS AND CURRENT THERAPEUTIC CHALLENGES

HemaSphere, 2022
M. Al-Jadiry, H. Ghali, I. Aref, A. Hatem, S. Faraj, S. Abdulrazzaq, R. Majid, A. Fadhil, S. Al-Hadad   +8 more
doaj   +1 more source

A case of fenitrothion self-poisoning with prolonged clinical features

Toxicology Communications
Background Organophosphorus compounds cause toxicity, typically within a few hours following oral exposure, by inhibiting acetylcholinesterase. We report a case of fenitrothion ingestion with delayed onset of severe muscarinic symptoms.Case report A 56 ...
Kaiho Hirata, Takuyo Chiba, Steven Bird, Naoki Shida, Koji Yamaguchi, Daisuke Yajima, Koji Masuda, Takashi Shiga   +7 more
doaj   +1 more source