Results 171 to 180 of about 2,120,854 (294)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Welfare indicators for young dairy heifers managed with virtual fencing in northern Sweden. [PDF]

JDS Commun
Liffen K, Vaccargiu G, Ren K, Oliveira J, Hetta M, Chagas JCC.   +5 more
europepmc   +1 more source

Mental Experiences in Wild Animals: Scientifically Validating Measurable Welfare Indicators in Free-Roaming Horses. [PDF]

Animals (Basel), 2023
Harvey AM, Beausoleil NJ, Ramp D, Mellor DJ.   +3 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Welfare stigma with decreasing employability [PDF]

We analyze the effects of income support on unemployment and welfare dynamics when stigma is attached to welfare provision. Stigma has been modeled in the literature as a cost of welfare participation; in this paper we analyze the effect of income ...
Dalit Contini, Matteo Richiardi
core  

The Primate Welfare INdicators project (PWIN): For an objective and standardised welfare assessment of non-human primates used in research. [PDF]

Anim Welf
Caspar-Cohen J, Demellier J, Pellé S, Valenchon M, Ravel S, Romain A, Petit O.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Comparative Analysis of Abattoir-Based Measures and On-Farm Pig Welfare Indicators in Italian Fattening Heavy Pigs. [PDF]

Vet Sci
Scuri L, Recchia M, Scali F, Romeo C, Maisano AM, Santucci G, Allegri C, Masserdotti M, Tenuzzo M, Ianieri A, Ghidini S, Alborali GL.   +11 more
europepmc   +1 more source

Erratum: Welfare of dairy cows in Kosovo and intervention thresholds for selected welfare indicators as suggested by farmers and veterinarians - ERRATUM. [PDF]

Anim Welf, 2023
Zhitia E, Leeb C, Muji S, Winckler C.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source