Results 251 to 260 of about 2,883,415 (350)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Effects of Raga music and Chinese five-element on milk production, antioxidant, neuroendocrine, immune, and welfare indicators in dairy cows. [PDF]

Front Vet Sci
Cao Z, Zhao H, Feng Z, Yang B, Li Z, Ma X, Gu S, Ma N.   +7 more
europepmc   +1 more source

Traumatic Injuries Detected during Post-Mortem Slaughterhouse Inspection as Welfare Indicators in Poultry and Rabbits. [PDF]

Animals (Basel), 2021
Valkova L, Voslarova E, Vecerek V, Dolezelova P, Zavrelova V, Weeks C.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Effects of Free-Range Systems on Muscle Fiber Characteristics and Welfare Indicators in Geese. [PDF]

Animals (Basel)
Wang G, Chen J, Guo Y, Weng K, Zhang Y, Zhang Y, Chen G, Xu Q, Chen Y.   +8 more
europepmc   +1 more source

Physiological welfare indicators in wild cetaceans: Epidermal cortisol and oxytocin concentrations in stranded striped dolphins

Clara Agustí, Laia Guix, Annaïs Carbajal, Mariano Domingo, Manel López‐Béjar, Xavier Manteca, Oriol Talló-Parra   +6 more
openalex   +1 more source

Effects of different enrichment devices on some welfare indicators of post-weaned undocked piglets

, 2016
Eleonora Nannoni, Luca Sardi, Marika Vitali, Erminio Trevisi, Anna Rita Ferrari, Francesca Barone, Maria Laura Bacci, S. Barbieri, Giovanna Martelli   +8 more
openalex   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Differences between behavioral time budget and welfare indicators in two different slow-growing broiler genotypes kept in the free-range system. [PDF]

Vet Res Commun
Sözcü A, İpek A, Gunnarsson S.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source