Results 121 to 130 of about 1,927,814 (300)

Employment Outcomes in the Welfare State [PDF]

open access: yes
We examine the implications of tax and subsidy policies for employment in the "three worlds of welfare", Anglo-Saxon, Continental European and Scandinavian. We argue that home production is key to a proper evaluation of the employment outcomes.
Christopher A. Pissarides   +1 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

O mito do declíneo do Welfare State (The myth of the decline of the Welfare State)

open access: yesEmancipação, 2009
Resumo: Os impactos do atual processo de globalização nas políticas sociais e no futuro do Estado de Bem-Estar Social são motivos de grande controvérsia no meio acadêmico, especialmente no Brasil.
Clóvis Roberto Zimmermann   +1 more
doaj  

Corporate Welfare [PDF]

open access: yes, 2002
A CCH policy brief investigating corporate welfare at the state and federal levels. Finds that taxpayer dollars supporting corporations that do not contribute to the public welfare might be better spent in addressing our nation's critical social issues ...
Les Brown
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The welfare state reader

open access: yesCaderno CRH, 2009
Clóvis Zimmermann, Amílcar Baiardi
doaj   +1 more source

The determinants of social spending in Spain (1880-1960): Is Lindert right? [PDF]

open access: yes
The main objective of this paper is to analyse the origins of the welfare state in Spain using the theoretical framework designed by Peter Lindert.
Margarita Vilar Rodriguez   +1 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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