Results 121 to 130 of about 252,893 (266)

Double Disadvantage in a Nordic Welfare State: A Demographic Analysis of the Single-Parent Employment Gap in Finland, 1987-2018. [PDF]

Eur J Popul, 2023
Härkönen J, Jalovaara M, Lappalainen E, Miettinen A.   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Finland's New Children's Hospital and resurgent charity in a Nordic post-welfare state. [PDF]

Med Humanit
Alava H, Lindroos J, Pihlman A.
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Childbirth in Early Swedish Television: From Promotion to Criticism of the Welfare State. [PDF]

J Med Humanit
Björklund E.
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Mapping a Shadow Carceral Welfare State:

Nordisk Tidsskrift for Kriminalvidenskab, 2022
Jonna Rennerskog
doaj   +1 more source

Basic Income and the Status of Women in an Established Gender-Equal Welfare State: Results from the Finnish Basic Income Experiment. [PDF]

Int J Environ Res Public Health, 2023
Kangas O, Ylikännö M.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Partisan Influence on Policy Preferences in Retrenching the Welfare State. [PDF]

Public Opin Q
Nemčok M, Wass H, Vesa J.
europepmc   +1 more source