Results 191 to 200 of about 1,936,269 (327)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Multidimensional Civic Engagement in Later Life in 32 European Countries-an Exploration of the Roles of Socio-Structural Resources and Welfare State Commitment. [PDF]

Res Aging
Näsman M, Nyqvist F, Nygård M, Vercauteren T, Dury S, Serrat R.   +5 more
europepmc   +1 more source

Book Review: G otz Aly, Hitler’s Beneficiaries: Plunder, Racial War, and the Nazi Welfare State

, 2008
Wendy C. Hamblet
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Life Conditions as Mediators of Welfare State Effect on Mental Wellbeing among Oldest Old in Europe. [PDF]

Int J Environ Res Public Health, 2022
Cresswell-Smith J, Wahlbeck K, Kalseth J.   +2 more
europepmc   +1 more source

Availability of social services for families with disabled children in the context of the welfare state

, 2021
Agota Giedre Raišienė, Laura Gardziulevičienė   +1 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The impact of child type 1 diabetes on parental incomes in a welfare state context: quasi-experimental evidence from Swedish national registers. [PDF]

Diabetologia
Kennedy B, Wernroth ML, Langenskiöld S, Bonander C, Byberg L, Grönqvist E, Fall T.   +6 more
europepmc   +1 more source

The welfare state in really hard times: Political trust and satisfaction with the German healthcare system during the COVID-19 pandemic. [PDF]

J Eur Soc Policy, 2022
Busemeyer MR.
europepmc   +1 more source

University-State Child Welfare Training Partnerships: The Challenge of Matching Dollar Contributions [PDF]

, 2013
Jerry D. Marx, Melissa Wells
openalex   +1 more source